5/23/2022

Children's Hospital of Philadephia

Research Fellow: Novel Therapeutics for Bleeding Disorder Program (Dr. Samelson-Jones)

About Us

We’re seeking breakthrough makers! Children’s Hospital of Philadelphia was built on the belief that we can change lives. Today, in every role throughout our hospital, research institute and care network, the 22,000 members of our workforce are finding new ways – big and small – to make a difference for the patients and families we serve. If you are ready to challenge yourself, be inspired and grow – no matter what your role – you just may be the kind of breakthrough maker who will thrive at CHOP. ​CHOP is proud to share that we are ranked No. 1 on Forbes' 2022 list of America's Best Large Employers!

Job Summary

The Novel Therapeutics for Bleeding Disorder (NoT Bleeding) Program is an institutionally funded effort at the Children’s Hospital of Philadelphia (CHOP) Research Institute to develop new, more effective treatments for patients with bleeding disorders and integrate novel therapies safely into clinical practice. Translational research projects are focused on the use of monoclonal antibodies, gene addition, and gene editing and will be conducted in the laboratories of Dr. Rodney Camire, Benjamin Samelson-Jones, and Lindsey George with extensive collaborations between the groups. Experimental approaches include recombinant protein production and purification, biochemical studies, mammalian and induced pluripotent stem cell culture, AAV vectors, and murine hemostatic models.

The postdoctoral fellow (postdoc) will have a terminal degree PhD, MD, or MD-PhD and will, under the direction/guidance of a mentor (Dr. Samelson-Jones, MD, PhD), assume responsibility for a specific, ongoing research project focused on understanding the interaction between activated factor VIII and IX and how it can be bypassed as a treatment for hemophilia B. The postdoc experience will serve to extend, refine, and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research and will contribute directly to the overall research goals of the project and the research group.  Postdocs will be expected to participate in/lead project planning, recording and interpretation/evaluation of data, and communication of results. Postdocs will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions, and presentations at national meetings.  Postdoctoral fellows also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

Program information

The Not Bleeding Frontier Program (https://www.chop.edu/get-involved/frontier-programs) will provide an ideal training environment for scientists interested in translational research. The Samelson-Jones laboratory is part of the Division of Hematology at CHOP and the Raymond G. Perelman Center for Cellular and Molecular Therapeutics (https://ccmt.research.chop.edu) that includes a team of investigators committed to developing protein, cell, and gene therapy approaches to treat genetic disease, including hemophilia.

Job Responsibilities

  • Conduct independent scholarly research and develop new methods and protocols
  • Participate in project planning, recording and evaluation of data
  • Acquire technical, lab management and grant writing skills
  • Participate in seminars, lectures, poster sessions and presentation at national meetings
  • Supervise junior lab members
  • Assist with other research projects

Required Licenses, Certifications, Registrations

Required Education and Experience

  • A terminal degree PhD, MD, DVM, etc.
  • According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing

Preferred Education, Experience & Cert/Lic

Additional Technical Requirements

To carry out its mission, it is of critical importance for the Children’s Hospital of Philadelphia (CHOP) to keep our patients, families and workforce safe and healthy and to support the health of our global community. In keeping with this, CHOP has mandated all workforce members on site at any CHOP location for any portion of their time be vaccinated for COVID-19 as a condition of employment.  This mandate also applies to workforce members performing work for CHOP at non-CHOP locations. Additionally, all workforce members based in or regularly scheduled to work at any New Jersey location are mandated to be both vaccinated and boosted for COVID-19, with booster timing consistent with applicable guidelines. The CHOP COVID-19 vaccine mandate is in alignment with applicable local, state and federal mandates. CHOP also requires all workforce members who work in patient care buildings or who provide patient care to receive an annual influenza vaccine. Employees may request exemption consideration for CHOP vaccine requirements for valid religious and medical reasons.  Please note start dates may be delayed until candidates are fully immunized or valid exemption requests are reviewed. In addition, candidates other than those in positions with regularly scheduled hours in New Jersey, must attest to not using tobacco products.

EEO / VEVRAA Federal Contractor

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